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A depressant, or central depressant, is a drug that lowers neurotransmission levels, which is to depress or reduce arousal or stimulation, in various areas of the brain. Depressants are also occasionally referred to as “downers” as they lower the level of arousal when taken. Stimulants or “uppers” increase mental and/or physical function, hence the opposite drug class of depressants is stimulants, not antidepressants. Depressants are widely used throughout the world as prescription medicines and as illicit substances. Alcohol is a very prominent depressant. Alcohol can be and is more likely to be a large problem among teenagers and young adults. When depressants are used, effects often include ataxia, anxiolysis, pain relief, sedation or somnolence, and cognitive/memory impairment, as well as in some instances euphoria, dissociation, muscle relaxation, lowered blood pressure or heart rate, respiratory depression, and anticonvulsant effects, and even similar effects of General Anaesthesia and/or death at high doses. Cannabis may sometimes be considered a depressant. THC may slow brain function to a small degree while reducing reaction to stimuli. Cannabis may also treat insomnia, anxiety and muscle spasms similar to other depressive drugs. Other depressants can include drugs like Xanax (a benzodiazepine) and a number of opiates. Depressants exert their effects through a number of different pharmacological mechanisms, the most prominent of which include facilitation of GABA, and inhibition of glutamatergic or monoaminergic activity. Other examples are chemicals that modify the electrical signaling inside the body. The most prominent of these being bromides and channel blockers.see more at WikipediaCheck More at http://CBproAds.com/clickbankstorefront/v4/sf.asp?id=4123832