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Castration anxiety is the fear of emasculation in both the literal and metaphorical sense. Castration anxiety is an overwhelming fear of damage to, or loss of, the penis; one of Sigmund Freud’s earliest psychoanalytic theories. Although Freud regarded castration anxiety as a universal human experience, few empirical studies have been conducted on the topic. Much of the research that has been done on the topic was done decades ago, although still relevant today. The theory is that a child has a fear of damage being done to their genitalia by the parent of the same sex (e.g. a son being afraid of his father) as punishment for sexual feelings toward the parent of the opposite sex (e.g. a son toward his mother). It has been theorized that castration anxiety begins between the ages of 3 and 5, otherwise known as the phallic stage of development according to Freud. Although typically associated with males, castration anxiety is theorized to be experienced in differing ways for both the male and female sexes.

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Horizon is a current and long-running BBC popular science and philosophy documentary programme. Series one was broadcast in 1964 and as of October 2016 is in its 52nd series. Over 1200 episodes have been broadcast (including specials) with an average of 24 episodes per series during the 52-year run. 1964–1969 – 135 episodes 1970–1979 – 299 episodes 1980–1989 – 234 episodes 1990–1999 – 220 episodes 2000–2009 – 193 episodes Since 2010 – 126 episodes

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Vaginal lubrication is a naturally produced fluid that lubricates a woman’s vagina. Vaginal lubrication is always present, but production increases significantly near ovulation and during sexual arousal in anticipation of sexual intercourse. Vaginal dryness is the condition in which this lubrication is insufficient, and sometimes artificial lubricants are used to augment it. Without sufficient lubrication, sexual intercourse can be painful. The vaginal lining has no glands, and therefore the vagina must rely on other methods of lubrication. Plasma from vaginal walls due to vascular engorgement is considered to be the chief lubrication source, and the Bartholin’s glands, located slightly below and to the left and right of the introitus (vaginal opening), also secrete mucus to augment vaginal-wall secretions. Near ovulation, cervical mucus provides additional lubrication.

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General anaesthesia or general anesthesia (see spelling differences) is a medically induced coma with loss of protective reflexes, resulting from the administration of one or more general anaesthetic agents. It is carried out to allow medical procedures that would otherwise be intolerably painful for the patient; or where the nature of the procedure itself precludes the patient being awake. A variety of drugs may be administered, with the overall aim of ensuring unconsciousness, amnesia, analgesia, loss of reflexes of the autonomic nervous system, and in some cases paralysis of skeletal muscles. The optimal combination of drugs for any given patient and procedure is typically selected by an anaesthetist, or another provider such as an operating department practitioner, anaesthetist practitioner, physician assistant or nurse anaesthetist (depending on local practice), in consultation with the patient and the surgeon, dentist, or other practitioner performing the operative procedure.

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Night sweats, also known as nocturnal hyperhidrosis, is the occurrence of excessive sweating during sleep. The person may or may not also perspire excessively while awake. One of the most common causes of night sweats in women over 40 is the hormonal changes related to menopause and perimenopause. This is a very common occurrence during the menopausal transition years. While night sweats might be relatively harmless, it can also be a sign of a serious underlying disease. It is important to distinguish night sweats due to medical causes from those that occur simply because the sleep environment is too warm, either because the bedroom is unusually hot or because there are too many covers on the bed. Night sweats caused by a medical condition or infection can be described as “severe hot flashes occurring at night that can drench sleepwear and sheets, which are not related to the environment”. Some of the underlying medical conditions and infections that cause these severe night sweats can be life-threatening and should promptly be investigated by a medical practitioner.

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Hypochondriasis or hypochondria is a condition in which a person is excessively and unduly worried about having a serious illness. An old concept, its meaning has repeatedly changed due to redefinitions in its source metaphors. It has been claimed that this debilitating condition results from an inaccurate perception of the condition of body or mind despite the absence of an actual medical diagnosis. An individual with hypochondriasis is known as a hypochondriac. Hypochondriacs become unduly alarmed about any physical or psychological symptoms they detect, no matter how minor the symptom may be, and are convinced that they have, or are about to be diagnosed with, a serious illness.Often, hypochondria persists even after a physician has evaluated a person and reassured them that their concerns about symptoms do not have an underlying medical basis or, if there is a medical illness, their concerns are far in excess of what is appropriate for the level of disease. Many hypochondriacs focus on a particular symptom as the catalyst of their worrying, such as gastro-intestinal problems, palpitations, or muscle fatigue. To qualify for the diagnosis of hypochondria the symptoms must have been experienced for at least 6 months.The DSM-IV-TR defines this disorder, “Hypochondriasis”, as a somatoform disorder and one study has shown it to affect about 3% of the visitors to primary care settings. The 2013 DSM-5 replaced the diagnosis of hypochondriasis with the diagnoses of “somatic symptom disorder” and “illness anxiety disorder”.Hypochondria is often characterized by fears that minor bodily or mental symptoms may indicate a serious illness, constant self-examination and self-diagnosis, and a preoccupation with one’s body. Many individuals with hypochondriasis express doubt and disbelief in the doctors’ diagnosis, and report that doctors’ reassurance about an absence of a serious medical condition is unconvincing, or short-lasting. Additionally, many hypochondriacs experience elevated blood pressure, stress, and anxiety in the presence of doctors or while occupying a medical facility, a condition known as “white coat syndrome”. Many hypochondriacs require constant reassurance, either from doctors, family, or friends, and the disorder can become a debilitating challenge for the individual with hypochondriasis, as well as his or her family and friends. Some hypochondriacal individuals completely avoid any reminder of illness, whereas others frequently visit medical facilities, sometimes obsessively. Some sufferers may never speak about it.

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In the Night Garden… is a BBC children’s television series, aimed at children aged from one to six years old. It is produced by Ragdoll Productions. Andrew Davenport created, wrote, and composed the title theme and incidental music for all 100 episodes. It was produced by Davenport and Anne Wood, the team that also co-created Teletubbies. The programme is narrated by Derek Jacobi. It is filmed mostly in live action, and features a mix of actors in costume, puppetry and computer animation. The characters include Iggle Piggle, Makka Pakka, Upsy Daisy, the Tombliboos, the Pontipines / the Wottingers, the Haahoos, the Ninky Nonk and the Pinky Ponk. The series was announced in October 2006, and twenty episodes were first broadcast in 19 March 2007. Two series were made, with 100 episodes in all. The BBC confirmed in 2010 that it would not be commissioning another series. The show’s budget was £14.5 million. The programme’s creators have said that it is designed to relax and entertain its intended audience of one to six-year-olds.

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Fragile X syndrome (FXS) is a genetic disorder. Symptoms often include mild to moderate intellectual disability. Physical features may include a long and narrow face, large ears, flexible fingers, and large testicles. About a third of those affected have features of autism such as problems with social interactions and delayed speech. Hyperactivity is common and seizures occur in about 10%. Males are usually more affected than females.Fragile X syndrome is typically due to an expansion of the CGG triplet repeat within the Fragile X mental retardation 1 (FMR1) gene on the X chromosome. This results in not enough fragile X mental retardation protein (FMRP), which is required for normal development of the connection between neurons. Diagnosis is by genetic testing to determine the number of CGG repeats in the FMRI gene. Normal is between 5 and 40 repeats, fragile X syndrome occurs with more than 200, and a premutation is said to be present when a middle number of repeats occurs. Testing for premutation carriers may allow for genetic counseling.There is no cure. Early intervention is recommended as it provides the most opportunity for developing a full range of skills. These interventions may include special education, speech therapy, physical therapy, or behavioral therapy. Medications may be used to treat associated seizures, mood problems, aggressive behavior, or ADHD. Fragile X syndrome occurs in about 1 in 4,000 males and 1 in 8,000 females.

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